Ultrastructural changes of optic nerve in experimental model of eye contusion in rabbits

Authors

  • N. E. Dumbrova SI "The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine"; Odesa (Ukraine)
  • T. A. Krasnovid SI "The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine"; Odesa (Ukraine)
  • V. V. Vit SI "The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine"; Odesa (Ukraine)
  • N. I. Molchanuk SI "The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine"; Odesa (Ukraine)
  • N. P. Grubnik SI "The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine"; Odesa (Ukraine)

DOI:

https://doi.org/10.31288/oftalmolzh201438993

Keywords:

optic nerve, contusion of the eyeball, ultrastructural changes

Abstract

Introduction: Direct and indirect injuries can lead to decrease of visual acuity in the eye or head traumas.

Purpose: To study ultrastructure of the optic nerve of rabbits after experimental mild contusion.

Material and methods: We examined 20 eyes. Electron microscopy of the op¬tic nerve was made after experimental mild eye contusion in 1 week, 1 month, 2 months.

Results: Postcontusional disorders were found in neurofilaments, neurotubules, axonal mitochondria.

Conclusion: Early and first ultrastructural changes of the optic nerve were found in experimental mild eye contusion in 1 week, 1 month, 2 months. The main disor¬ders were found in neurofilaments, neurotubules, axonal mitochondria.

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Published

2026-07-27

How to Cite

[1]
Dumbrova, N.E. et al. 2026. Ultrastructural changes of optic nerve in experimental model of eye contusion in rabbits. Ukrainian Journal of Ophthalmology . 3 (Jul. 2026), 89–93. DOI:https://doi.org/10.31288/oftalmolzh201438993.

Issue

Section

Experimental Studies

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