Correlation between optical coherence tomography angiography-based data and postoperative visual acuity in patients that underwent surgery for macula-on RRD and macula-off RRD
DOI:
https://doi.org/10.31288/oftalmolzh202334248Keywords:
rhegmatogenous retinal detachment, retinal microcirculation, optical coherence tomography angiography, macular-off retinal detachmentAbstract
Background: Despite advances in surgical techniques for rhegmatogenous retinal detachment (RRD) repair, patients are still at high risk for low functional outcomes. Given the above, it is important to find reasons for disappointment at the outcomes of vitreoretinal surgery for RRD. Impaired retinal microcirculation is a possible cause of insufficiently good functional outcomes in surgery for RRD.
Purpose: To compare postoperative optical coherence tomography angiography (OCTA)-based changes in retinal microcirculation in the eyes of patients that underwent surgery for macula-on RRD versus the eyes of patients that underwent surgery for macula-off RRD and (2) to establish a relationship between OCTA data and best-corrected visual acuity (BCVA).
Material and Methods: This prospective study included 116 patients. Of these, 65 underwent surgery for macular-on RRD (group 1) and 51, surgery for macular-off RRD (group 2). OCTA-based retinal vasculature parameters (foveal avascular zone (FAZ) area, parafoveal superficial capillary plexus (SCP) density and deep capillary plexus (DCP) density, vessel diameter, and vessel tortuosity index (VTI)) and their correlation with BCVA were assessed. Follow-up duration was 12 months.
Results: In group 1, there was a negative correlation between the FAZ area and the macular thickness (r = - 0.299, p = 0.025) at month 12. The final BCVA was associated with the parafoveal DCP density (r = - 0.340, p = 0.010) and FAZ area (r= 0.390, p = 0.003). At 12 months, in group 2, the BCVA negatively correlated with the FAZ area (r = - 0.408, p = 0.012) and parafoveal SCP density (r = - 0.451, p = 0.005). In addition, there was a negative correlation between the parafoveal DCP density and the postoperative BCVA (r = - 0.418). There was no correlation between the FAZ area and the macular thickness (r = - 0.282, p = 0.080).
Conclusion: The poorer vessel tortuosity index and parafoveal vessel density and diameter, the lower was postoperative visual acuity.
References
Feltgen N, Walter P. Rhegmatogenous retinal detachment. An ophthalmologic emergency. Dtsch. Arztebl. Int. 2014, 111, 12-22. https://doi.org/10.3238/arztebl.2014.0012
Kuhn F, Aylward B. Rhegmatogenous retinal detachment: a reappraisal of its pathophysiology and treatment. Ophthalmic Res. 2014; 51(1):15-31. https://doi.org/10.1159/000355077
Park D, Choi K, Sun H, Lee S. Factors associated with visual outcome after macula-off rhegmatogenous retinal detachment surgery. Retina. 2018; 38(1):137-147 https://doi.org/10.1097/IAE.0000000000001512
Vail D, Al-Moujahed A, Timing and Reoperation Rate of Rhegmatogenous Retinal Detachments Occurring During Major Ophthalmology Meetings. Ophthalmic Surgery, Lasers and Imaging Retina. 2020;51(6):328-337. https://doi.org/10.3928/23258160-20200603-03
Chekalina NI, Shut SV, Trybrat TA, Manusha YI, Kazakov YM. Effect of quercetin on parameters of central hemodynamics and myocardial ischemia in patients with table coronary heart disease. Wiadomoscilekarskie. 2017; 70(4):707-711.
Inooka D, Ueno S, Quantification of Macular Microvascular Changes in Patients With Retinitis Pigmentosa Using Optical Coherence Tomography Angiography. Invest Ophthalm & Vis Sci. 2018, January 59: 433-438. https://doi.org/10.1167/iovs.17-23202
Moir J, Khanna S, Skondra D. Review of OCT Angiography Findings in Diabetic Retinopathy: Insights and Perspectives. Int. J. Transl. Med. 2021, 1(3), 286-305. https://doi.org/10.3390/ijtm1030017
Bonfiglio V, Ortisi E. Vascular changes after vitrectomy for rhegmatogenous retinal detachment: optical coherence tomography angiography study. Acta Ophthalmol. 2019, 98(5):e563-569 https://doi.org/10.1111/aos.14315
Woo JM, Yoon YS, Woo JE, Min JK (2018) foveal avascular zone area changes analyzed using OCT angiography after successful rhegmatogenous retinal detachment repair. Curr Eye Res. 2018, 43(5):674-678 https://doi.org/10.1080/02713683.2018.1437922
Danese, С., Lanzetta, Р. Optical Coherence Tomography Findings in Rhegmatogenous Retinal Detachment: A Systematic Review. Journal of Clinical Medicine. 2022; 11 (19), 5819. https://doi.org/10.3390/jcm11195819
Wang H, Xu X, Sun X, Ma Y, Sun T Macular perfusion changes assessed with optical coherence tomography angiography after vitrectomy for rhegmatogenous retinal detachment. Graefes Arch Clin Exp Ophthalmol. 2019,257(4):733-740 https://doi.org/10.1007/s00417-019-04273-7
Nam S, Kim K, Kim E, Yu S. Longitudinal microvascular changes on optical coherence tomographic angiography after macula-off rhegmatogenous retinal detachment repair surgery. Ophthalmologica. 2021, 244(1):34-41 https://doi.org/10.1159/000508464
McKay K, Vingopoulos F, Wang J, Papakostas T. Retinal microvasculature changes after repair of macula-off retinal detachment assessed with optical coherence tomography angiography. Clinical Ophthalmology. 2020, 14:1759-1767 https://doi.org/10.2147/OPTH.S214623
Roohipoor R, Tayebi F, Riazi-Esfahani H. (2020) Optical coherence tomography angiography changes in macula-off rhegmatogenous retinal detachments repaired with silicone oil. International Ophthalmology. 2020, 40(12):3295-3302. https://doi.org/10.1007/s10792-020-01516-z
Tsen C, Sheu S, Chen S. Wu TT Imaging analysis with optical coherence tomography angiography after primary repair of macula-off rhegmatogenous retinal detachment. Graefes Arch Clin Exp Ophthalmol. 2019, 257(9):1847-1855 https://doi.org/10.1007/s00417-019-04381-4
Xu C, Wu J, Feng C. Changes in the postoperative foveal avascular zone in patients with rhegmatogenous retinal detachment associated with choroidal detachment. International Ophthalmology. 2020, 40(10):2535-2543. https://doi.org/10.1007/s10792-020-01433-1
Yui N, Kunikata H, Aizawa N, Nakazawa T. Optical coherence tomography angiography assessment of the macular capillary plexus after surgery for macula-off rhegmatogenous retinal detachment. Graefes Arch Clin Exp Ophthalmol. 2019, 257(1):245-248 https://doi.org/10.1007/s00417-018-4133-3
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