Combined Treatment for Recurrent Herpetic Stromal Keratitis with Ulceration: a Case Report

Authors

  • L.F. Troychenko SI "The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine"; Odesa (Ukraine)
  • T.B. Gaydamaka SI "The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine"; Odesa (Ukraine)
  • G.I. Drozhzhyna SI "The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine"; Odesa (Ukraine)

DOI:

https://doi.org/10.31288/oftalmolzh201916164

Keywords:

herpetic keratitis, treatment

Abstract

Herpes simplex keratitis (HSK) is a severe ophthalmic pathology which comprises 20-50% of inflammatory diseases in the cornea. Since keratitis is characterized by a long-term duration, severity, and a tendency to recurrence, studies on ophthalmic herpes and searches for new treatments are of great relevance. 

Our clinical case demonstrated successful combined treatment of a recurrent stromal herpetic corneal lesion with ulceration. Both treatments, conservative (complex etiotropic, anti-viral, anti-inflammatory, and nutrition-improving) and surgical (an onlay technique), were successful. At 12 months after surgery, the patients had no pain syndrome; the corneal surface was epithelialized. No recurrence of herpetic keratitis was observed. 

Thus, a combination of etiotropic pathogenic treatment and AM transplantation appears to be effective for severe long-lasting recurrent herpetic keratitis with the presence of defects on the corneal surface.

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Published

2025-11-14

How to Cite

[1]
Troychenko, L. et al. 2025. Combined Treatment for Recurrent Herpetic Stromal Keratitis with Ulceration: a Case Report. Ukrainian Journal of Ophthalmology . 1 (Nov. 2025), 61–64. DOI:https://doi.org/10.31288/oftalmolzh201916164.

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