Efficacy of a novel non-contact corneal esthesiometer in assessing the neurotrophic status of the cornea in T1DM patients with bacterial keratitis
DOI:
https://doi.org/10.31288/oftalmolzh201962933Keywords:
algesimeter, non-contact corneal esthesiometer, diabetes mellitus, bacterial keratitisAbstract
Purpose: To develop a novel non-contact corneal esthesiometer and to determine the efficacy of this meter in assessing the neurotrophic status of the cornea in type I diabetic mellitus (T1DM) patients with bacterial keratitis.
Material and Methods: We developed a novel non-contact corneal esthesiometer and determined the efficacy of this meter in assessing the neurotrophic status of the cornea based on examination of 30 T1DM patients with bacterial keratitis and 30 healthy individuals.
Results: A corneal sensitivity assessment technique using our novel non-contact corneal esthesiometer was found to be non-invasive, accurate and repeatable. The use of low-temperature air jets in non-contact esthesiometry results in improved accuracy. Corneal sensitivity examination at nine specified points and calculation of mean corneal sensitivity threshold allows for a more comprehensive corneal function assessment, with account of the peripheral cornea.
Conclusion: A significantly decreased corneal sensitivity was found in T1DM patients with bacterial keratitis. Our newly developed non-contact corneal esthesiometer was found to be effective in assessing the neurotrophic status of the cornea in T1DM patients with bacterial keratitis.
References
1.Vieira-Potter VJ, Karamichos D, Lee DJ. Ocular complications of diabetes and therapeutic approaches. Biomed Res Int. 2016;2016:3801570. https://doi.org/10.1155/2016/3801570
2.Bikbova G, Oshitari T, Baba T, Yamamoto S. Neuronal Changes in the Diabetic Cornea: Perspectives for Neuroprotection. Biomed Res Int. 2016;2016:5140823.https://doi.org/10.1155/2016/5140823
3.Von Frey M. Berichte uber die verhaindlungen der koniglich sachsichen. Ges Wiss. 1894;46:185-96.
4.Cochet P, Bonnet R. L'esthesie corneenne. La Clin Ophtalmol. 1960;4:3-27.
5.Radzikhovski? BL, Luchik VI. [Corneal sensitivity and its diagnostic value in ocular and systemic disease]. Kyiv: Zdorov'ia; 1974. Russian.
6.Golebiowski B, Papas E, Stapleton F. Assessing the sensory function of the ocular surface: implications of use of a non-contact air jet aesthesiometer versus the Cochet-Bonnet aesthesiometer. Exp Eye Res. 2011; 92:408-13. [PubMed: 21376718]https://doi.org/10.1016/j.exer.2011.02.016
7.Murphy PJ, Patel S, Marshall J. A new non-contact corneal aesthesiometer (NCCA). Ophthal Physiol Opt. 1996;16:101-7.https://doi.org/10.1046/j.1475-1313.1996.95001026.x
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