Changes in ciliary body thickness over time following preoperative anti-inflammatory treatment in rhegmatogenous retinal detachment complicated by ciliochoroidal detachment
DOI:
https://doi.org/10.31288/oftalmolzh201562328Keywords:
rhegmatogenous retinal detachment, retinal detachment, ciliochoroidal detachment, ciliary body edema, triamcinolone acetonide, perfluoropropaneAbstract
Background: Rhegmatogenous retinal detachment (RRD), if complicated by ciliochoroidal detachment (CCD), is accompanied by marked hypotony and intraocular inflammation. However, to the best of our knowledge, there is no literature on the state of the ciliary body, its role in the development of this pathology, and specificity of the changes in it following the treatment aimed at resolving concomitant inflammation and choroidal attachment.
Purpose: To assess the anatomical position and thickness of the ciliary body and to investigate the changes in the latter over time following anti-inflammatory pre-vitrectomy treatment in RRD complicated by CCD.
Materials and Methods: Forty-three patients (43 eyes) with RRD complicated by CCD underwent standard ophthalmological examination (including assessment of the level of visual acuity, biomicroscopy, ophthalmoscopy and ocular tonometry) and ultrasound biomicroscopy of the ciliary body, choroid and retina both before and following anti-inflammatory pre-vitrectomy treatment.
Results: At the baseline, all subject eyes had ciliary body edema and ciliary body detachment extending into the choroid. In ciliary body detachment, the morphological features of the ciliary body included ciliary body edema and disorganization of the supraciliary layer of the pars plana, which was evident by the presence of multiple small oblique fibers. In all subject eyes, the treatment resulted in the achievement of reattachment of the choroid and the ciliary body as well as a reduction in ciliary body edema (total mean ciliary thickness reduced from 0.83 ± 0.09 to 0.65 ± 0.09 mm, with a difference of 0.18 ± 0.07 mm, P < 0.001).
Conclusion: Preoperative anti-inflammatory treatment in RRD complicated by CCD resulted in restoration of the anatomical position of the ciliary body and a statistically significant reduction in ciliary body edema.
References
Wilkinson CP, Rice TA. Michels's Retinal Detachment. 2nd ed. St. Louis: Mosby; 1997:979 -1079 p.
Zhu J, Xu X, Zhang X. Surgical therapeutic results of rhegmatogenous retinal detachment associated with choroidal detachment. Zhonghua Yan Ke Za Zhi. 2002 Mar;38(3):135-9.
Brazitikos PD, Androudi S, Christen WG, Stangos NT. Primary pars plana vitrectomy versus scleral buckle surgery for the treatment of pseudophakic retinal detachment: a randomized clinical trial. Retina. 2005 Dec;25(8):957-64 https://doi.org/10.1097/00006982-200512000-00001
Sharma T, Gopal L, Reddy RK et al. Primary vitrectomy for combined rhegmatogenous retinal detachment and choroidal detachment with or without oral corticosteroids: a pilot study. Retina. 2005 Feb-Mar;25(2):152-7. https://doi.org/10.1097/00006982-200502000-00006
Duan AL, Wang JZ, Wang NL. The pilot study of intravitreal injection of triamcinolone acetonide for treatment of retinal detachment with choroidal detachment. Zhonghua Yan Ke Za Zhi. 2005 Jul;41(7):606-9.
Levitskaya GV, Abdoulkhadi M. Indications and scheme for preoperative pretreatment in combined treatment of rhegmatogenous retinal detachment complicated by choroidal detachment. Oftalmologiya. 2013;2(12):58-64. Russian.
Levitskaya GV, Putiienko AA, Abdoulkhadi M. Efficacy of new method of treatment of rhegmatogenous retinal detachment complicated by choroidal detachment. Problems of Environmental and Medical Genetics and Clinical Immunology. 2013;6(120):270-81. Ukrainian.
Shen L, Mao J, Sun S, et al. Perioperative pharmacological management of choroidal detachment associated with rhegmatogenous retinal detachment. Acta Ophthalmol. 2015 Feb 23. doi: 10.1111/aos.12694. [Epub ahead of print]. https://doi.org/10.1111/aos.12694
Levitskaya GV, Koval'chuk AG, Pasyechnikova NV. State of ciliary body in retinal detachment complicated by ciliochoroidal detachment. Oftalmol Zh. 2015;3:42-9. Russian. https://doi.org/10.31288/oftalmolzh201534246
Jarret WH. Rhegmatogenous retinal detachment complicated by severe intraocular inflammation, hypotony, and choroidal detachment. Trans Am Ophthalmol Soc. 1981;79:664-83.
Glantz SA. Primer of Biostatistics. 4th ed. [Transl. from English]. Moscow: Praktika;1998. 459 p. Russian
Gundorova RA, Chentsova EV, Leparskaya NL et al. Ultrasound biomicroscopy and laser Doppler fluorometry study of the ciliary body in traumatic retinal detachment due to ocular contusion. Rus Ophthalm J. 2012;3:14-8. Russian
Yang JG, Yao GM, Li SP et al. Surgical treatment for 42 patients with traumatic annular ciliochoroidal detachment. Int J Ophthalmol. 2011;4(1):81-4.
Eroshevskii TI. Primary glaucoma and postoperative complications. Oftalmol Zh. 1976;31(6):403-7. Russian
Tanaka A, Emi K, Danjo S. Choroidal detachment associated with rhegmatogenous retinal detachment and aqueous flare. Nippon Ganka Gakkai Zasshi. 1991 Dec;95(11):1129-34.
Tsuboi S, Taki-Noie J, Emi K, et al. Fluid dynamics in eyes with rhegmatogenous retinal detachments. Am J Ophthalmol. 1985 Jun 15;99(6):673-6. https://doi.org/10.1016/S0002-9394(14)76034-9
Smedt S., Sullivan P. Massive choroidal detachment masking overlying primary rhegmatogenous retinal detachment: A case series. Bull Soc Belge Ophtalmol. 2001;(282):51-5.
Seelenfreund MH, Kraushar MF, Schepens CL et al. Choroidal detachment associated with primary retinal detachment. Arch Ophthalmol. 1974 Apr;91(4):254-8. https://doi.org/10.1001/archopht.1974.03900060264003
Kawana K, Okamoto F, Hiraoka T et al. Ciliary body edema after scleral buckling surgery for rhegmatogenous retinal detachment. Ophthalmology. 2006; 113(1):36-41. https://doi.org/10.1016/j.ophtha.2005.09.023
Pavlin CJ, Rutnin SS, Devenyi R et al. Supraciliary effusions and ciliary body thickening after scleral buckling procedures. Ophthalmology. 1997 Mar;104(3):433-8. https://doi.org/10.1016/S0161-6420(97)30295-4
Perez RN, Phelps CS, Burton TC. Angle closure glaucoma following scleral buckling operations. Trans Am Acad Ophthalmol Otolaryngol. 1976;81:247-52.
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