Our experience of laser iridotomy in patients with chronic angle closure glaucoma

Authors

  • R. M. Lopadchak Danylo Halytsky Lviv National Medical University
  • I. Ia. Novytskyy Danylo Halytsky Lviv National Medical University
  • Ya. Z. Fedus Danylo Halytsky Lviv National Medical University

DOI:

https://doi.org/10.31288/oftalmolzh202261013

Keywords:

chronic angle closure glaucoma, laser peripheral iridotomy, gonioscopy, phacoemulification, goniosynechialysis, anterior chamber angle, optical coherence tomography angiography

Abstract

Background: Determining the strategy of surgical treatment for chronic angle closure glaucoma (CACG) is still important.

Purpose: To assess the efficacy, rates of successful intraocular pressure (IOP) lowering and the increase in anterior chamber angle for laser peripheral iridotomy (LPI) in patients with CACG.

Material and Methods: We examined 31 patients (31 eyes; 18 women and 13 men) who had undergone LPI for CACG. Patient age ranged from 49 to 77 years (mean age, 64.8 ± 5.3 years). The indication for LPI was an anterior chamber angle of Shaffer grade 2 to 3 and the presence of optic neuropathy. Mean Maklakoff intraocular pressure (IOP) was 23.4 ± 1.2 mmHg.

Results: Thirteen patients required surgery during the follow-up after LPI. Particularly, 10 eyes required phacoemulsification (PHACO) only, and 3 eyes, PHACO plus goniosynechialysis (GSL), because of decompensated IOP and an anterior chamber angle narrower than Shaffer grade 2 by gonioscopy. Kaplan-Meier survival analysis showed that the rates of successful IOP lowering for laser peripheral iridotomy (without the need for surgery, PHACO alone or PHACO plus GSL) at 12 months, 24 months and 36 months were 87.1%, 71.0% and 58.06%, respectively.

Conclusion: The LPI is effective for opening the anterior chamber angle and reducing IOP over 6 months, but is less effective and does not allow opening the anterior chamber angle over a period exceeding 6 months. The LPI may be considered as a preparatory procedure in CACG, particularly in the presence of an acute angle-closure glaucoma attack in the fellow eye.

Keywords: chronic angle closure glaucoma, laser peripheral iridotomy, gonioscopy, phacoemulification, goniosynechialysis, anterior chamber angle optical coherence tomography

References

1.Quigley HA, Broman AT. The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol. 2006 Mar;90(3):262-7. https://doi.org/10.1136/bjo.2005.081224

2.Tham Y-C, Li X, Wong TY, Quigley HA, Aung T, Cheng C-Y. Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis.

3.Ophthalmology. 2014 Nov;121(11):2081-90. https://doi.org/10.1016/j.ophtha.2014.05.013

4.Peng PH, Nguyen H, Lin HS, et al. Long-term outcomes of laser iridotomy in Vietnamese patients with primary angle closure. Br J Ophthalmol. 2011;95(9):1207-1211. https://doi.org/10.1136/bjo.2010.181016

5.Rao A, Rao HL, Kumar AU, Babu JG, Madhulata U, Arthi J, et al. Outcomes of Laser Peripheral Iridotomy in Angle Closure Disease. Semin Ophthalmol. 2013;28:4e8. https://doi.org/10.3109/08820538.2012.702260

6.Chen MJ, Cheng CY, Chou CK, et al. The long-term effect of Nd:YAG laser iridotomy on intraocular pressure in Taiwanese eyes with primary angle-closure glaucoma. J Chin Med Assoc 2008;71:300-4. https://doi.org/10.1016/S1726-4901(08)70126-6

7.Аlsagoff Z, Aung T, Ang LP, Chew PT. Long-term clinical course of primary angle-closure glaucoma in an Asian population. Ophthalmology. 2000;107:2300-4. https://doi.org/10.1016/S0161-6420(00)00385-7

8.Chew PT, Aung T. Primary angle-closure glaucoma in Asia. J Glaucoma. 2001;10(suppl):S7- 8. https://doi.org/10.1097/00061198-200110001-00004

Published

2025-08-27

How to Cite

1.
Lopadchak RM, Novytskyy II, Fedus YZ. Our experience of laser iridotomy in patients with chronic angle closure glaucoma . J.ophthalmol. (Ukraine) [Internet]. 2025 Aug. 27 [cited 2025 Aug. 28];(6):10-3. Available from: https://ua.ozhurnal.com/index.php/files/article/view/307

Issue

Section

Clinical Ophthalmology

Similar Articles

<< < 1 2 3 4 5 6 7 8 9 > >> 

You may also start an advanced similarity search for this article.