Use of keratoxenoimplant for therapeutic and therapeutic-and-tectonic keratoplasty in severe ocular burns and corneal ulcerations of various etiologies

Authors

  • N.V. Pasyechnikova SI "The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine"; Odesa (Ukraine)
  • S.A. Iakymenko SI "The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine"; Odesa (Ukraine)
  • M.V. Turchyn Horbachevsky Ternopil State Medical University
  • O.I. Buznyk SI "The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine"; Odesa (Ukraine)
  • P.O. Kostenko SI "The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine"; Odesa (Ukraine)

DOI:

https://doi.org/10.31288/oftalmolzh201551317

Keywords:

keratoxenoimplant, ocular burn, corneal inflammatory diseases

Abstract

Background: The acute shortage of human donor corneas for transplantation has emerged, setting ophthalmologists a task of searching for new graft materials for use in keratoplasty.

Purpose: To investigate the possibility of using the keratoxenoimplant for therapeutic or therapeutic-and-tectonic keratoplasty in ocular burns or ulcerative sequelae of corneal inflammatory diseases.

Materials and Methods: A clinical study of the use of the keratoxenoimplant was performed in 69 eyes (60 patients) with ocular burns or ulcerative sequelae of corneal inflammatory diseases.

Results: In all eyes of the study, the keratoxenoimplant was found to facilitate the preservation of the globe and light perception. In some patients, following a number of rehabilitative-and-reconstructive procedures, we managed to implant the keratoprosthesis and to restore sight (in some cases to the visual acuity of 0.5). 

Conclusion: The results provide the basis for recommendation of the keratoxenoimplant for wide use if human donor material is not easily available.

References

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Published

2026-07-13

How to Cite

[1]
Pasyechnikova, N. et al. 2026. Use of keratoxenoimplant for therapeutic and therapeutic-and-tectonic keratoplasty in severe ocular burns and corneal ulcerations of various etiologies. Ukrainian Journal of Ophthalmology . 5 (Jul. 2026), 13–17. DOI:https://doi.org/10.31288/oftalmolzh201551317.

Issue

Section

Clinical Ophthalmology

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