COVID-19-associated cavernous sinus thrombosis: a case report
DOI:
https://doi.org/10.31288/oftalmolzh202126971Keywords:
COVID-19, ocular symptoms of COVID-19, COVID-19-associated coagulopathy, cavernous sinus thrombosisAbstract
This paper describes a case of cavernous sinus thrombosis. The condition developed in a patient who had been treated for confirmed COVID-19. Left eye examination findings were as follows: amaurosis; absence of periorbital skin sensation; signs of orbital cellulitis; ptosis; chemosis; total ophthalmoplegia; exophthalmos; decreased corneal sensation; widened pupil; and absence of pupil light reflex. In addition, ophthalmoscopy showed diffused retinal and optic disc edema. The patient had an atypical clinical course which could not be clearly identified as septic or aseptic, and his elevated D-dimer level could indicate a potential relationship between this condition and COVID-19.
References
1.Al-Ani F, Chehade S., Lazo-Langner A. Thrombosis risk associated with COVID-19 infection. A scoping review. Thromb Res. 2020 Aug;192:152-60. https://doi.org/10.1016/j.thromres.2020.05.039
2.Panigada M, Bottino N, Tagliabue P, Grasselli G, Novembrino C, Chantarangkul V, at al. Hypercoagulability of COVID-19 patients in intensive care unit: a report of thromboelastography findings and other parameters of hemostasis. J Thromb Haemost. 2020;18(7):1738-42. https://doi.org/10.1111/jth.14850
3.Al-Samkari H, Karp Leaf RS, Dzik WH, Carlson JC, Fogerty AE, Waheed A, et al. COVID and coagulation: bleeding and thrombotic manifestations of SARS-CoV2 infection. Blood. 2020 Jul 23;136(4):489-500. https://doi.org/10.1182/blood.2020006520
4.Hughes C, Nichols T, Pike M, Subbe C, Elghenzai S. Cerebral venous sinus thrombosis as a presentation of COVID-19. Eur J Case Rep Intern Med. 2020 Apr 29;7(5):001691. https://doi.org/10.12890/2020_001691
5.Silvis SM, Sousa DAD, Ferro JM, Coutinho JM. Cerebral venous thrombosis. Nat Rev Neurol. 2017 Sep;13(9):555-65. https://doi.org/10.1038/nrneurol.2017.104
6.Oripov OI, Bilalov EN, Umarov RZ. [COVID-19-associated cavernous sinus thrombosis]. Vestnik Tashkentskoi medicinskoi akademii (spetsial'nyi vypusk). 2020:34-42.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 О. И. Орипов, Э. Н. Билалов

This work is licensed under a Creative Commons Attribution 4.0 International License.
This work is licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) that allows users to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author as long as they cite the source.
COPYRIGHT NOTICE
Authors who publish in this journal agree to the following terms:
- Authors hold copyright immediately after publication of their works and retain publishing rights without any restrictions.
- The copyright commencement date complies the publication date of the issue, where the article is included in.
DEPOSIT POLICY
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) during the editorial process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work with an acknowledgement of its initial publication in this journal.
- Post-print (post-refereeing manuscript version) and publisher's PDF-version self-archiving is allowed.
- Archiving the pre-print (pre-refereeing manuscript version) not allowed.