Vitrectomy and high-frequency welding-assisted endoresection оf retinal vasoproliferative tumors: a case series
DOI:
https://doi.org/10.31288/oftalmolzh202421318Keywords:
vasoproliferartive tumor, high-frequency electric welding of biolohical tissuesAbstract
Background: The relative rarity of retinal vasoptoliferative tumors has resulted in a lack of ecidence-based consensus agreement on how best to treat these lesions. Therefore, there is a need for advanced techniques capable of more effective treatment of these tumors and allowing for the preservation of visual function.
Purpose: To review the results of treatment of large retinal VPTs by pars plana vitrectomy with tumor endoresection and the use of high-frequency electric welding (HFEW) for achieving hemostasis.
Material and Methods: We reivewed the results of surgical treatment of large retinal VPTs complicated by exudative retinal detachment, macular edema, and/or epiretinal fibrosis in 5 patients (6 eyes).
Patients underwent a comprehensive eye examination (visual acuity, biomicroscopy, ophthalmoscopy, tonometry, perimetry) and imaging (ultrasound examination, and optical coherence tomography. Outcome measures included anatomical success (retinal re-attachment), visual acuity, the presence of intraoperative and postoperative hemorrhagic complications, resorption of subretinal exudates, restoration of retinal profile, and the absence of tumor recurrence over the 6-month follow-up period.
Results: Total tumor removal was achieved in all cases. In addition, there was no intraoperative hemorrhage. At the 6-month follow-up examination, the best-corrected visual acuity (BCVA) ranged from 0.17 to 0.3. Over the 6-month follow-up period, the retina remained re-attached, BCVA improved, and partial resorption of hard exudates as well as restoration of the retinal profile was observed in all cases (6 eyes). Moreover, no tumor recurrence was noted.
Conclusion: Vitrectomy with retinal VPT endoresection results in positive anatomical and functional outcomes, making it a method of choice in the treatment of large complicated retinal VPT resistant to more eye-sparing modalities; the HFEW technique proved to be an apt choice for intraoperative hemostasis.
References
Baines PS, Hiscott PS, McLeod D. Posterior non-vascularized proliferative extra retinopathy and peripheral nodular retinal telangiectasis. Trans Ophthalmol Soc UK (1962). 1982;102 (Pt 4):487-91.
Shields JA, Decker WL, Sanborn GE, Augsburger JJ, Goldberg RE. Presumed acquired retinal hemangiomas. Ophthalmology. 1983 Nov;90(11):1292-300. https://doi.org/10.1016/S0161-6420(83)34389-X
Galinos SO, Smith TR, Brockhurst RJ. Angioma-like lesion in hemoglobin sickle cell disease. Ann Ophthalmol. 1979 Oct;11(10):1549-52.
Campochiaro PA, Conway BP. Hemangiomalike masses of the retina. Arch Ophthalmol. 1988 Oct;106(10):1409-13. https://doi.org/10.1001/archopht.1988.01060140573025
Laqua H, Wessing A. Peripheral retinal telangiectasis in adults simulating a vascular tumor or melanoma. Ophthalmology. 1983 Nov;90(11):1284-91. https://doi.org/10.1016/S0161-6420(83)34390-6
Irvine F, O'Donnell N, Kemp E, Lee WR. Retinal vasoproliferative tumors: surgical management and histological findings. Arch Ophthalmol. 2000 Apr;118(4):563-9. https://doi.org/10.1001/archopht.118.4.563
Shields CL, Shields JA, Barrett J, De Potter P. Vasoproliferative tumors of the ocular fundus. Classification and clinical manifestations in 103 patients. Arch Ophthalmol. 1995 May;113(5):615-23. https://doi.org/10.1001/archopht.1995.01100050083035
Honavar SG. Retinal vasoproliferative tumor - A proposal for classification. Indian J Ophthalmol. 2018 Feb;66(2):185-186 https://doi.org/10.4103/ijo.IJO_128_18
Shields CL, Kaliki S, Al-Dahmash S, Rojanaporn D, Shukla SY, Reilly B, Shields JA. Retinal vasoproliferative tumors: comparative clinical features of primary vs secondary tumors in 334 cases. JAMA Ophthalmol. 2013 Mar;131(3):328-34. https://doi.org/10.1001/2013.jamaophthalmol.524
Chu TW, Tsai SH, Chen LJ. Retinal vasoproliferative tumor regression after intravitreal aflibercept. Taiwan J Ophthalmol. 2022 May 30;13(2):249-252. https://doi.org/10.4103/tjo.tjo_21_22
Rennie IG. Retinal vasoproliferative tumours. Eye (Lond). 2010 Mar;24(3):468-71. https://doi.org/10.1038/eye.2009.305
Rodrigues LD, Serracarbassa LL, Rosa H, Nakashima Y, Serracarbassa PD. Tumor vasoproliferativo associado à tuberculose ocular presumida: relato de caso [Vasoproliferative tumor associated with presumed ocular tuberculosis: case report]. Arq Bras Oftalmol. 2007 May-Jun;70(3):527-31. Portuguese. https://doi.org/10.1590/S0004-27492007000300025
Heimann H, Bornfeld N, Vij O, Coupland SE, Bechrakis NE, Kellner U, Foerster MH. Vasoproliferative tumours of the retina. Br J Ophthalmol. 2000 Oct;84(10):1162-9. https://doi.org/10.1136/bjo.84.10.1162
Anastassiou G, Bornfeld N, Schueler AO, Schilling H, Weber S, Fluehs D, Jurklies B, Vij O, Sauerwein W. Ruthenium-106 plaque brachytherapy for symptomatic vasoproliferative tumours of the retina. Br J Ophthalmol. 2006 Apr;90(4):447-50. https://doi.org/10.1136/bjo.2005.081422
Umanets MM. [Influence of high-frequency welding of the biological tissues on duration of bleeding from the main vessels of the retina in modeling intraocular bleeding in rabbits in comparison with diathermocoagulation]. Oftalmol Zh. 2012;4:88-91. https://doi.org/10.31288/oftalmolzh201248891
Umanets NN, Pasyechnikova NV, Naumenko VA, Maletskyi AP, Chabotarev EP, Pukhlik ES. Endoresection of choroidal melanoma using high-frequency electric welding of biological tissues. J Ophthalmol (Ukraine). 2016;4:11-14. https://doi.org/10.31288/oftalmolzh201641114
Umanets NN, Lakiza AV. [Use of high-frequency electric welding for achieving hemostasis in hemangioma endoresection during vitrectomy in patients with von Hippel-Lindau syndrome]. Tavricheskii mediko-biologicheskii vestnik. 2013;16(63):145-8. Russian.
Paton BE, Krivtsun IV, Marinsky GS, Khudetsky IYu, Lankin YuN, Chernets AV. [Welding, cutting and heat treatment of live tissues]. The Paton welding journal. 2013;10-11:135-46. Russian. Available at: http://nbuv.gov.ua/UJRN/as_2013_10-11_22.
Hussain RN, Jmor F, Damato B, Heimann H. Verteporfin Photodynamic Therapy for the Treatment of Retinal Vasoproliferative Tumors. Ophthalmology. 2015 Nov;122(11):2361-3. https://doi.org/10.1016/j.ophtha.2015.05.026
Yeh S, Wilson DJ. Pars plana vitrectomy and endoresection of a retinal vasoproliferative tumor. Arch Ophthalmol. 2010 Sep;128(9):1196-9. https://doi.org/10.1001/archophthalmol.2010.194
Pasyechnikova NV, editor; Filatov institute of eye diseases and tissue therapy. [High-frequency welding of biological tissues in ophthalmology: a monograph]. Odesa: Chornomor'ia; 2018. Ukrainian.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Микола Уманець, Інна
This work is licensed under a Creative Commons Attribution 4.0 International License.
This work is licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) that allows users to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author as long as they cite the source.
COPYRIGHT NOTICE
Authors who publish in this journal agree to the following terms:
- Authors hold copyright immediately after publication of their works and retain publishing rights without any restrictions.
- The copyright commencement date complies the publication date of the issue, where the article is included in.
DEPOSIT POLICY
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) during the editorial process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work with an acknowledgement of its initial publication in this journal.
- Post-print (post-refereeing manuscript version) and publisher's PDF-version self-archiving is allowed.
- Archiving the pre-print (pre-refereeing manuscript version) not allowed.