Vitrectomy and high-frequency welding-assisted endoresection оf retinal vasoproliferative tumors: a case series

Authors

  • M.M. Umanets SI "The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine"
  • I.P. Dovgan SI "The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine" https://orcid.org/0000-0001-8204-1436
  • M. I. Marushchak I. Horbachevsky Ternopil National Medical University
  • I.Y. Krynytska I. Horbachevsky Ternopil National Medical University

DOI:

https://doi.org/10.31288/oftalmolzh202421318

Keywords:

vasoproliferartive tumor, high-frequency electric welding of biolohical tissues

Abstract

Background: The relative rarity of retinal vasoptoliferative tumors has resulted in a lack of ecidence-based consensus agreement on how best to treat these lesions. Therefore, there is a need for advanced techniques capable of more effective treatment of these tumors and allowing for the preservation of visual function.

Purpose: To review the results of treatment of large retinal VPTs by pars plana vitrectomy with tumor endoresection and the use of high-frequency electric welding (HFEW) for achieving hemostasis.

Material and Methods: We reivewed the results of surgical treatment of large retinal VPTs complicated by exudative retinal detachment, macular edema, and/or epiretinal fibrosis in 5 patients (6 eyes).

Patients underwent a comprehensive eye examination (visual acuity, biomicroscopy, ophthalmoscopy, tonometry, perimetry) and imaging (ultrasound examination, and optical coherence tomography. Outcome measures included anatomical success (retinal re-attachment), visual acuity, the presence of intraoperative and postoperative hemorrhagic complications, resorption of subretinal exudates, restoration of retinal profile, and the absence of tumor recurrence over the 6-month follow-up period.

Results: Total tumor removal was achieved in all cases. In addition, there was no intraoperative hemorrhage. At the 6-month follow-up examination, the best-corrected visual acuity (BCVA) ranged from 0.17 to 0.3. Over the 6-month follow-up period, the retina remained re-attached, BCVA improved, and partial resorption of hard exudates as well as restoration of the retinal profile was observed in all cases (6 eyes). Moreover, no tumor recurrence was noted.

Conclusion: Vitrectomy with retinal VPT endoresection results in positive anatomical and functional outcomes, making it a method of choice in the treatment of large complicated retinal VPT resistant to more eye-sparing modalities; the HFEW technique proved to be an apt choice for intraoperative hemostasis.

References

Baines PS, Hiscott PS, McLeod D. Posterior non-vascularized proliferative extra retinopathy and peripheral nodular retinal telangiectasis. Trans Ophthalmol Soc UK (1962). 1982;102 (Pt 4):487-91.

Shields JA, Decker WL, Sanborn GE, Augsburger JJ, Goldberg RE. Presumed acquired retinal hemangiomas. Ophthalmology. 1983 Nov;90(11):1292-300. https://doi.org/10.1016/S0161-6420(83)34389-X

Galinos SO, Smith TR, Brockhurst RJ. Angioma-like lesion in hemoglobin sickle cell disease. Ann Ophthalmol. 1979 Oct;11(10):1549-52.

Campochiaro PA, Conway BP. Hemangiomalike masses of the retina. Arch Ophthalmol. 1988 Oct;106(10):1409-13. https://doi.org/10.1001/archopht.1988.01060140573025

Laqua H, Wessing A. Peripheral retinal telangiectasis in adults simulating a vascular tumor or melanoma. Ophthalmology. 1983 Nov;90(11):1284-91. https://doi.org/10.1016/S0161-6420(83)34390-6

Irvine F, O'Donnell N, Kemp E, Lee WR. Retinal vasoproliferative tumors: surgical management and histological findings. Arch Ophthalmol. 2000 Apr;118(4):563-9. https://doi.org/10.1001/archopht.118.4.563

Shields CL, Shields JA, Barrett J, De Potter P. Vasoproliferative tumors of the ocular fundus. Classification and clinical manifestations in 103 patients. Arch Ophthalmol. 1995 May;113(5):615-23. https://doi.org/10.1001/archopht.1995.01100050083035

Honavar SG. Retinal vasoproliferative tumor - A proposal for classification. Indian J Ophthalmol. 2018 Feb;66(2):185-186 https://doi.org/10.4103/ijo.IJO_128_18

Shields CL, Kaliki S, Al-Dahmash S, Rojanaporn D, Shukla SY, Reilly B, Shields JA. Retinal vasoproliferative tumors: comparative clinical features of primary vs secondary tumors in 334 cases. JAMA Ophthalmol. 2013 Mar;131(3):328-34. https://doi.org/10.1001/2013.jamaophthalmol.524

Chu TW, Tsai SH, Chen LJ. Retinal vasoproliferative tumor regression after intravitreal aflibercept. Taiwan J Ophthalmol. 2022 May 30;13(2):249-252. https://doi.org/10.4103/tjo.tjo_21_22

Rennie IG. Retinal vasoproliferative tumours. Eye (Lond). 2010 Mar;24(3):468-71. https://doi.org/10.1038/eye.2009.305

Rodrigues LD, Serracarbassa LL, Rosa H, Nakashima Y, Serracarbassa PD. Tumor vasoproliferativo associado à tuberculose ocular presumida: relato de caso [Vasoproliferative tumor associated with presumed ocular tuberculosis: case report]. Arq Bras Oftalmol. 2007 May-Jun;70(3):527-31. Portuguese. https://doi.org/10.1590/S0004-27492007000300025

Heimann H, Bornfeld N, Vij O, Coupland SE, Bechrakis NE, Kellner U, Foerster MH. Vasoproliferative tumours of the retina. Br J Ophthalmol. 2000 Oct;84(10):1162-9. https://doi.org/10.1136/bjo.84.10.1162

Anastassiou G, Bornfeld N, Schueler AO, Schilling H, Weber S, Fluehs D, Jurklies B, Vij O, Sauerwein W. Ruthenium-106 plaque brachytherapy for symptomatic vasoproliferative tumours of the retina. Br J Ophthalmol. 2006 Apr;90(4):447-50. https://doi.org/10.1136/bjo.2005.081422

Umanets MM. [Influence of high-frequency welding of the biological tissues on duration of bleeding from the main vessels of the retina in modeling intraocular bleeding in rabbits in comparison with diathermocoagulation]. Oftalmol Zh. 2012;4:88-91. https://doi.org/10.31288/oftalmolzh201248891

Umanets NN, Pasyechnikova NV, Naumenko VA, Maletskyi AP, Chabotarev EP, Pukhlik ES. Endoresection of choroidal melanoma using high-frequency electric welding of biological tissues. J Ophthalmol (Ukraine). 2016;4:11-14. https://doi.org/10.31288/oftalmolzh201641114

Umanets NN, Lakiza AV. [Use of high-frequency electric welding for achieving hemostasis in hemangioma endoresection during vitrectomy in patients with von Hippel-Lindau syndrome]. Tavricheskii mediko-biologicheskii vestnik. 2013;16(63):145-8. Russian.

Paton BE, Krivtsun IV, Marinsky GS, Khudetsky IYu, Lankin YuN, Chernets AV. [Welding, cutting and heat treatment of live tissues]. The Paton welding journal. 2013;10-11:135-46. Russian. Available at: http://nbuv.gov.ua/UJRN/as_2013_10-11_22.

Hussain RN, Jmor F, Damato B, Heimann H. Verteporfin Photodynamic Therapy for the Treatment of Retinal Vasoproliferative Tumors. Ophthalmology. 2015 Nov;122(11):2361-3. https://doi.org/10.1016/j.ophtha.2015.05.026

Yeh S, Wilson DJ. Pars plana vitrectomy and endoresection of a retinal vasoproliferative tumor. Arch Ophthalmol. 2010 Sep;128(9):1196-9. https://doi.org/10.1001/archophthalmol.2010.194

Pasyechnikova NV, editor; Filatov institute of eye diseases and tissue therapy. [High-frequency welding of biological tissues in ophthalmology: a monograph]. Odesa: Chornomor'ia; 2018. Ukrainian.

Published

2024-05-01

How to Cite

1.
Umanets M, Dovgan I, Marushchak MI, Krynytska I. Vitrectomy and high-frequency welding-assisted endoresection оf retinal vasoproliferative tumors: a case series. J.ophthalmol. (Ukraine) [Internet]. 2024 May 1 [cited 2024 Nov. 23];(2):13-8. Available from: http://ua.ozhurnal.com/index.php/files/article/view/129

Issue

Section

Clinical Ophthalmology