Anatomical and topographical features of filtering blebs after non-penetrating deep sclerectomy in patients with glaucoma according to optical coherence tomography
DOI:
https://doi.org/10.31288/oftalmolzh201443439Keywords:
optical coherence tomography (OCT), open-angle glaucoma, non-penetrating deep sclerectomy (HBSEg)Abstract
Purpose. To study morphological changes that occur in the filter cushion after non-perforating deep sclerectomy with optical coherence tomography. Materials and methods. The study involved 31 patients (31 eyes) with diagnosis of primary open- angle glaucoma of 2—3 degree. There were 20 men and 11 women. The average age of patients was 63. The apparatus of the company Heidelberg SPECTRALIS OCT + HRA was used to carry out optical coherence tomography; the study period made up 14—357 days after the operation. There were valuated: height, wall thickness, the size of the subconjunctival cavity, echogenicity inside the cushion, and the topographical interrelation between the scleral flap, the sclera and the conjunctival cushion.
Results. Depending on the tonography data the patients were divided into 2 groups with compensation of the intraocular pressure — Po within 14—18 mm Hg and with decompensation Po > 22 mm Hg (without the use of hypotensive drugs). Filtering cushions were divided into 4 types: diffuse filtering cushion -51.6 % of cases; cystic -19.35 %; fibrous type — 12.9 % and 12.9 % of the hood-type. Postoperative intraocular pressure compensation was observed in the first two types of filtering cushions. Decompensation or partial compensation has been observed in the third and fourth types of filtering cushions.
Conclusions. The method of optical coherence tomography can detect signs of scarring processes in dynamics at the preclinical level and at any time after microin-vasive nonperforating operations for glaucoma, which enables prediction of the hypotensive effect. The absence of normalization of the intraocular pressure in the postoperative period is associated with the formation of certain types of filtering cushions that combine various decompensation risk factors. Risk factors should include the height of the filtering cushion, its limitation and echogenicity as well as reduction the height or lack of intrasclera cavity.
References
1. Belova LV, Balashevich LI, Somov EE, Naumenko VV.Immediate and long-term results of penetrating type operations in patients with open-angle glaucoma. Glaukoma. 2003;4:26-9. Russian.
2. Ivanova ES. Prevention of excessive reparative processes during glaucoma surgery: thesis for Candidate of Med. Science: 14.01.17. M.; 1999. 162 p. .
3. Kozlov VI, Kozlova EE, Sokolovskaya TV, Sidorova AV.Causes of increased intraocular pressure in the early and late periods after penetrating deep sclerectomy. Prospects for directions in the surgical treatment for glaucoma. M.;1997. 50-3.
4. Lebedev OI. The concept of excessive scarring after glaucoma surgeries. Vestn Oftalmol. 1993; 1:36-9. Russian.
5. Magaramov DA, Nersesov YuE. Pathogenetic mechanisms and efficacy of laser descemetogoniopuncture (DGP) in primary open-angle glaucoma. VIII Congress of Ophthalmologists of Ukraine: theses. M.; 2005. 194- 5.
6. Melyanchenko NB, Khatminskii YuF. The relationship between the rate of decompression of the eyeball and emerging vasomotor reactions in the vessels of the uveal tract. Vestn Oftalmol. 1988;5:29-31. Russian.
7. Takhchidi KhP. Opportunities of ultrasound biomicroscopy (UBM) in the assessment of the operation zone and choice of tactics in IOP decompensation after glaucoma filtering interventions. Fyodorov Memorial Lectures - 2006. Modern methods of diagnosis in ophthalmology. Anatomic and physiologic basis of visual organ pathology: Collection of papers. M.; 2006. 308-10.
8. Takhchidi EKh. Optical coherent tomography of the anterior segment of the eye and its application for assessing a zone of glaucoma surgery. IX All Russian Scientific practical conference with international participation «Fyodorv Memorial Lectures - 2011»: Collection oftheses. M.: Izd-vo «Oftalmologiia»; 2011. 410 p.
9. Takhchidi KhP, Takhchidi EKh, Novikov SV et al. Intrasurgical tactic prevention of scarring in the simulation of non-penetrating deep sclerectomy in the experiment in vivo. Oftalmokhirurgiia. 2012;4:56-60. Russian.
10. Uzunyan JG. Ultrasound biomicroscopy in assessing the efficacy of non-penetrating deep sclerectomy: thesis for Candidate of Med. Science. M.;2007. 150 p.
11. Farazhayeva EE, Egorova EV, Uzunyan DG. Ultrasound biomicroscopy of formed drainage outflow tract after non-perforating surgery in patients with high baseline of IOP. Oftalmokhirurgiia. 2012;4:61-7. Russian.
12. Dahan E, Drusedau MU. Nonpenetrating filtration surgery for glaucoma: control by surgery only. J. Cataract Refract. Surg. 2000;26(5):695-701. https://doi.org/10.1016/S0886-3350(00)00366-7
13. Ghasem Fakhraie, Sedigheh Kahansal, Yadollah Eslami et al. Correlation between Filtering BlebClinical Morphology, Anterior Segment Optical Coherence Tomography Findings, and Intraocular Pressure. Iranian Journal of Ophthalmology. 2011;23(4):21-8.
14. Kazuyuki Hirooka, Mai Takagishi, Tetsuya Baba, Hirokazu Takenaka and Fumio Shiraga Stratus optical coherence tomography study of filtering blebs after primary trabeculectomy with a fornix-based conjunctival flap.Department of Ophthalmology, Kagawa University Faculty of Medicine, Kagawa. Acta Ophtalmol. 2010;88:60- 4. https://doi.org/10.1111/j.1755-3768.2008.01401.x
15. Khaw PT, Occleston NL, Schultz G et al. Activation and suppression of fibroblast function. Eye. 1994;8:188- 95. https://doi.org/10.1038/eye.1994.44
16. Marchini G, Marraffa M, Brunelli C et al. Ultrasound biomicroscopy and intraocular-pressure-lowering mechanisms of deep sclerectomy with reticulated hy-aluronic acid implant. J. Cataract. Refract. Surg. 2001;27(4):507- 17. https://doi.org/10.1016/S0886-3350(00)00857-9
17. Mills KB. Trabeculectomy: a retrospective longterm follow-up of 444 cases. Br. J. Ophthalmol. 1981;65:790-5. https://doi.org/10.1136/bjo.65.11.790
18. Netland PA. Nonpenetrating glaucoma surgery. Ophthalmology. 2001;108(2):416-21. https://doi.org/10.1016/S0161-6420(00)00647-3
19. Vesti E. Filtering blebs: follow up of trabeculectomy. Ophthalmic. Surg. 1993;24:249- 55. https://doi.org/10.3928/1542-8877-19930401-06
20. Wells AP, Crowston JG, Marks J et al. A pilot study of a system for grading of drainage blebs after glaucoma surgery. J Glaucoma. 2004;13:454- 60. https://doi.org/10.1097/00061198-200412000-00005
21. Yamamoto T, Sakuma T, Kitazawa Y. An ultrasound biomicroscopic study of filtering blebs after mitomycin C. Ophthalmology. 1995;102:1770-6. https://doi.org/10.1016/S0161-6420(95)30795-6
22. Zhang Yi, Qiang Wu, Zhang Min et al. Evaluating subconjunctival bleb function after trabeculectomy using slitlamp optical coherence tomography and ultrasound biomicros-copy. Chin. Med. J. 2008;121(14):1274- 9. https://doi.org/10.1097/00029330-200807020-00005
Downloads
Published
Issue
Section
License
Copyright (c) 2026 С. А. Рыков, С. И. Косуба, С. А. Сук, Л. П. Тутченко, И. С. Косуба, О. А. Венедиктова

This work is licensed under a Creative Commons Attribution 4.0 International License.
This work is licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) that allows users to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author as long as they cite the source.
COPYRIGHT NOTICE
Authors who publish in this journal agree to the following terms:
- Authors hold copyright immediately after publication of their works and retain publishing rights without any restrictions.
- The copyright commencement date complies the publication date of the issue, where the article is included in.
DEPOSIT POLICY
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) during the editorial process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work with an acknowledgement of its initial publication in this journal.
- Post-print (post-refereeing manuscript version) and publisher's PDF-version self-archiving is allowed.
- Archiving the pre-print (pre-refereeing manuscript version) not allowed.








