Current optical methods for controlling progressive myopia control in children: a review

Authors

  • T.Ye. Tsybulska Zaporizhzhia State Medical and Pharmaceutical University, Zaporizhzhia, Ukraine; VIZUS LLC, Zaporizhzhia, Ukraine https://orcid.org/0000-0002-1745-7002
  • O.Yu. Titkova Zaporizhzhia State Medical and Pharmaceutical University, Zaporizhzhia, Ukraine; VIZUS LLC, Zaporizhzhia, Ukraine https://orcid.org/0009-0000-8551-0883

DOI:

https://doi.org/10.31288/oftalmolzh202515459

Keywords:

myopia, spectacles, soft contact lenses, orthokeratology lenses, axial length

Abstract

The prevalence of myopia has been steadily increasing worldwide. The role of optical methods for controlling progressive myopia control in children is still important. Therefore, the purpose of this study was to review current optical methods for controlling progressive myopia control in children. It is well established that myopic children wearing full optical correction are less prone to the progression of the disease. It has been reported that the undercorrected group of myopic school children showed a 1.3 times greater rate of progression over 24 months as compared to the fully corrected group. Correction of myopia with spectacles is common in children. Many clinicians share the opinion that myopic peripheral defocus has a positive effect on axial elongation, and peripheral defocus spectacles have been increasingly used for this purpose. Optical correction with spectacles, however, may have some disadvantages. Some children wearing spectacles may feel psychological discomfort due to negative peer comments and/or have problems with compliance. Soft contact lenses with myopic defocus and othokeratology (OK) lenses are of special value for myopia progression control. It has been reported that myopia progression was controlled by 38.6% and 66.6% in children wearing Multistage + 1.50D and Proclear +3.00D multifocal contact lenses, respectively, in comparison to children wearing single-vision control lenses over an 18-month period. Refractive therapy with orthokeratology lenses has become an increasingly popular technique for controlling the progression of myopia. It has been reported that orthokeratology lenses are more effective than spectacles or soft contact lenses at reducing myopia progression. The review provides evidence that myopia control devices utilizing the myopic defocus principle are the first-line means for optical correction in children with progressive myopia.

Author Biographies

T.Ye. Tsybulska , Zaporizhzhia State Medical and Pharmaceutical University, Zaporizhzhia, Ukraine; VIZUS LLC, Zaporizhzhia, Ukraine

Tamila Y. Tsybulska, Dr Sc (Med) and Professor,  Department of Ophthalmology, Zaporizhzhia State Medical and Pharmaceutical University; Ophthalmologist, VIZUS LLC, Zaporizhzhia, Ukraine

O.Yu. Titkova, Zaporizhzhia State Medical and Pharmaceutical University, Zaporizhzhia, Ukraine; VIZUS LLC, Zaporizhzhia, Ukraine

Oleksandra Y. Titkova, Post-Graduate Student, Department of Ophthalmology, Zaporizhzhia State Medical and Pharmaceutical University; Ophthalmologist, VIZUS LLC, Zaporizhzhia, Ukraine

References

Flitcroft DI, He M, Jonas JB, Jong M, Naidoo K, Ohno-Matsui K, et al. IMI - Defining and Classifying Myopia: A Proposed Set of Standards for Clinical and Epidemiologic Studies. Invest Ophthalmol Vis Sci. 2019 Feb 28;60(3):M20-M30. https://doi.org/10.1167/iovs.18-25957

Tsai TH, Liu YL, Ma IH, Su CC, Lin CW, Lin LL, et al. Evolution of the Prevalence of Myopia among Taiwanese Schoolchildren: A Review of Survey Data from 1983 through 2017. Ophthalmology. 2021 Feb;128(2):290-301. https://doi.org/10.1016/j.ophtha.2020.07.017

Moiseenko RO, Holubchykov MV, Mykhalchuk VM, Rykov SO. [Ophthalmological care in Ukraine for 2014-2017: analytical and statistical reference book]. Kropyvnytskyi: POLIUM; 2018. 314 p. Ukrainian.

Bezditko PA, Parhomets RA. [Analysis of the Influence of Corneal Parameters on the Pattern of Myopia Progression when Using Orthokeratology Lenses in Children]. Ophthalmology. 2021 Jun;2(13):56-63. Ukrainian. https://doi.org/10.30702/Ophthalmology30062021-13.2.39-46/17.7-05

Maliyeva EV, Bushueva NN. [Comparative analysis of morphometric parameters of the macular region of the retina in patients with different types of myopia]. Materials of the Scientific and Practical Conference with International Participation "Filatov Readings - 2016," May 19-20, 2016, Odessa, Ukraine; 194-195.Ukrainian.

Horbatyuk TL, Boichuk IM. [Morphostructural features of the optic nerve and peripapillary fibers in children with myopia]. Ophthalmological Journal. 2011;(1):41-44. Ukrainian.

Ulyanova NA. High axial myopia: pathogenesis, diagnostics, prevention, and treatment (clinical and experimental study). [Author's abstract of the dissertation for the degree of Doctor of Medical Sciences in the specialty 14.01.18 "Ophthalmology"]. Odesa, 2015. 32 p. Ukrainian.

Ulyanova NA, Burdeinyi SI. [Morphometric features of the choroid in patients with progressive myopia according to the SS-optical coherent tomography-angiography]. Ukrainian Archives of Ophthalmology. 2018;(1)10:52-56. doi:https://doi.org/10.22141/2309-8147.6.1.2018.172270.Ukrainian.

Grzybowski A, Kanclerz P, Tsubota K, Lanca C, Saw SM. A review on the epidemiology of myopia in school children worldwide. BMC Ophthalmol. 2020 Jan 14;20(1):27. https://doi.org/10.1186/s12886-019-1220-0

Lawrenson JG, Shah R, Huntjens B, Downie LE, Virgili G, Dhakal R, et al. Interventions for myopia control in children: a living systematic review and network meta-analysis. Cochrane Database Syst Rev. 2023 Feb 16;2(2):CD014758. https://doi.org/10.1002/14651858.CD014758.pub2

Yazdani N, Sadeghi R, Ehsaei A, Taghipour A, Hasanzadeh S, Zarifmahmoudi L, et al. Under-correction or full correction of myopia? A meta-analysis. J Optom. 2021 Jan-Mar;14(1):11-19. https://doi.org/10.1016/j.optom.2020.04.003

Chung K, Mohidin N, O'Leary DJ. Undercorrection of myopia enhances rather than inhibits myopia progression. Vision Res. 2002 Oct;42(22):2555-9. https://doi.org/10.1016/S0042-6989(02)00258-4

Walline JJ, Lindsley KB, Vedula SS, Cotter SA, Mutti DO, Ng SM, et al. Interventions to slow progression of myopia in children. Cochrane Database Syst Rev. 2020 Jan 13;1(1):CD004916. https://doi.org/10.1002/14651858.CD004916.pub4

Kang P, Swarbrick H. Peripheral refraction in myopic children wearing orthokeratology and gas-permeable lenses. Optom Vis Sci. 2011 Apr;88(4):476-82. https://doi.org/10.1097/OPX.0b013e31820f16fb

Rodenstock. Children's lenses from Rodenstock [Internet]. Germany: Rodenstock; 2024 Apr 19 [cited 2024 Dec 2]. Available from: https://www.rodenstock.com/lenses/childrens-lenses

Rodenstock. MyCon lenses from Rodenstock for myopia control in children [Internet]. Ukraine: Lens; [cited 2024 Dec 28]. Available from: https://lens.com.ua/ua/goods_for_know/linzi-mycon-vid-rodenstock-rozrobleni-dlya-kontrolyu-korotkozorosti/

Radhakrishnan H, Lam CSY, Charman WN. Multiple segment spectacle lenses for myopia control. Part 2: Impact on myopia progression. Ophthalmic Physiol Opt. 2023 Sep;43(5):1137-1144. https://doi.org/10.1111/opo.13194

Atchison DA, Charman WN. Optics of spectacle lenses intended to treat myopia progression. Optom Vis Sci. 2024 May 1;101(5):238-249. https://doi.org/10.1097/OPX.0000000000002140

Ohlendorf A, Rifai K, Boeck-Maier C, Ungewiss J, Lappe C, Li L, et al. Myopia control efficacy through Emmetropic Progression Ratio: 1-year of spectacle wear with cylindrical annular refractive elements (CARE). Invest Ophthalmol Vis Sci. 2024;65(7):127.

Kaphle D, Atchison DA, Schmid KL. Multifocal spectacles in childhood myopia: Are treatment effects maintained? A systematic review and meta-analysis. Surv Ophthalmol. 2020 Mar-Apr;65(2):239-249. https://doi.org/10.1016/j.survophthal.2019.10.001

Kearney S, Coverdale S, Saunders C, Day M, Rountree L, Webber K, et al. Perceptions and barriers to accessing myopia management in the UK. Children. 2024 Dec;11:1490. https://doi.org/10.3390/children11121490

Cooper J, OʼConnor B, Watanabe R, Fuerst R, Berger S, Eisenberg N, et al. Case Series Analysis of Myopic Progression Control With a Unique Extended Depth of Focus Multifocal Contact Lens. Eye Contact Lens. 2018 Sep;44(5):e16-e24. https://doi.org/10.1097/ICL.0000000000000440

Nakamura Y, Hieda O, Yokota I, Teramukai S, Sotozono C, Kinoshita S. Comparison of myopia progression between children wearing three types of orthokeratology lenses and children wearing single-vision spectacles. Jpn J Ophthalmol. 2021 Sep;65(5):632-643. https://doi.org/10.1007/s10384-021-00854-4

Ruiz-Pomeda A, Pérez-Sánchez B, Valls I, Prieto-Garrido FL, Gutiérrez-Ortega R, Villa-Collar C. MiSight Assessment Study Spain (MASS). A 2-year randomized clinical trial. Graefes Arch Clin Exp Ophthalmol. 2018 May;256(5):1011-1021. https://doi.org/10.1007/s00417-018-3906-z

Hieda O, Nakamura Y, Hiraoka T, Kojima M, Oshika T, Sotozono C. Clinical study on the effect of multifocal contact lenses on myopia progression in myopia school children : Multifocal contact lens study for suppression of myopia progression. Trials. 2021 Mar 31;22(1):239. https://doi.org/10.1186/s13063-021-05197-6

Walline JJ, Walker MK, Mutti DO, Jones-Jordan LA, Sinnott LT, Giannoni AG, et al. BLINK Study Group. Effect of High Add Power, Medium Add Power, or Single-Vision Contact Lenses on Myopia Progression in Children: The BLINK Randomized Clinical Trial. JAMA. 2020 Aug 11;324(6):571-580. https://doi.org/10.1001/jama.2020.10834

Bressler NM. Reducing the Progression of Myopia. JAMA. 2020 Aug 11;324(6):558-559. https://doi.org/10.1001/jama.2020.10953

Chamberlain P, Bradley A, Arumugam B, Hammond D, McNally J, Logan NS, et al. Long-term Effect of Dual-focus Contact Lenses on Myopia Progression in Children: A 6-year Multicenter Clinical Trial. Optom Vis Sci. 2022 Mar 1;99(3):204-212. https://doi.org/10.1097/OPX.0000000000001873

Raffa LH, Allinjawi K, Sharanjeet-Kaur, Akhir SM, Mutalib HA. Myopia control with soft multifocal contact lenses: 18-month follow-up. Saudi J Ophthalmol. 2022 Jun 13;35(4):325-331. https://doi.org/10.4103/1319-4534.347305

Lau JK, Vincent SJ, Cheung SW, Cho P. Higher-Order Aberrations and Axial Elongation in Myopic Children Treated With Orthokeratology. Invest Ophthalmol Vis Sci. 2020 Feb 7;61(2):22. https://doi.org/10.1167/iovs.61.2.22

Brennan NA, Toubouti YM, Cheng X, Bullimore MA. Efficacy in myopia control. Prog Retin Eye Res. 2021 Jul;83:100923. https://doi.org/10.1016/j.preteyeres.2020.100923

Lipson MJ, Boland B, McAlinden C. Vision-related quality of life with myopia management: A review. Cont Lens Anterior Eye. 2022 Jun;45(3):101538. https://doi.org/10.1016/j.clae.2021.101538

Sun L, Li ZX, Chen Y, He ZQ, Song HX. The effect of orthokeratology treatment zone decentration on myopia progression. BMC Ophthalmol. 2022 Feb 15;22(1):76. https://doi.org/10.1186/s12886-022-02310-4

Guo B, Cheung SW, Kojima R, Cho P. One-year results of the Variation of Orthokeratology Lens Treatment Zone (VOLTZ) Study: a prospective randomised clinical trial. Ophthalmic Physiol Opt. 2021 Jul;41(4):702-714. https://doi.org/10.1111/opo.12834

Bullimore MA, Johnson LA. Overnight orthokeratology. Cont Lens Anterior Eye. 2020 Aug;43(4):322-332. https://doi.org/10.1016/j.clae.2020.03.018

Song Y, Zhu S, Yang B, Wang X, Ma W, Dong G, Liu L. Accommodation and binocular vision changes after wearing orthokeratology lens in 8- to 14-year-old myopic children. Graefes Arch Clin Exp Ophthalmol. 2021 Jul;259(7):2035-2045. https://doi.org/10.1007/s00417-021-05106-2

Ding C, Chen Y, Li X, Huang Y, Chen H, Bao J. The associations of accommodation and aberrations in myopia control with orthokeratology. Ophthalmic Physiol Opt. 2022 Mar;42(2):327-334. https://doi.org/10.1111/opo.12930

Xiao J, Pan X, Hou C, Wang Q. Changes in Subfoveal Choroidal Thickness after Orthokeratology in Myopic Children: A Systematic Review and Meta-Analysis. Curr Eye Res. 2024 Jul;49(7):683-690. https://doi.org/10.1080/02713683.2024.2310618

Meng QY, Miao ZQ, Liang ST, Wu X, Wang LJ, Zhao MW, et al. Choroidal thickness, myopia, and myopia control interventions in children: a Meta-analysis and systemic review. Int J Ophthalmol. 2023 Mar 18;16(3):453-464. https://doi.org/10.18240/ijo.2023.03.17

Bezditko PA, Parkhomets RO. [The effect of pupil diameter on the axial length of the eye in children with myopia using orthokeratology lenses]. Archive of Ukrainian Ophthalm. 2021; 9(1): 6-9. Ukrainian. https://doi.org/10.22141/2309-8147.9.1.2021.229517

Wang B, Naidu RK, Qu X. Factors related to axial length elongation and myopia progression in orthokeratology practice. PLoS One. 2017 Apr 18;12(4):e0175913. https://doi.org/10.1371/journal.pone.0175913

Swarbrick HA, Alharbi A, Watt K, Lum E, Kang P. Myopia control during orthokeratology lens wear in children using a novel study design. Ophthalmology. 2015 Mar;122(3):620-30. https://doi.org/10.1016/j.ophtha.2014.09.028

Bushueva NN, Malieva EV. [Long-term outcomes of orthokeratology ttherapy in patients with myopia]. Ophthalmology Journal. 2015;1:45-49.Ukrainian.

Malieva EV. Optimization of diagnostics of different types of myopia based on morphometric and functional indicators of the visual organ. [Author's abstract of the dissertation for the degree of Candidate of Medical Sciences]. Odesa, 2016. 22 p.Ukrainian.

Parkhomenko HY, Mohylevskyi SY, Prysiazhna SV, Bilyk IA, Levytska TI. Experience of combined correction of high-degree myopia. (Doctoral dissertation). R45 "One's Childhood Must Be Seen21": 9th Scientific and Practical Conference of Pediatric Ophthalmologists and Optometrists of Ukraine with International Participation, June 10-12, 2021: Collection of Papers / Edited by Professor SO Rykov. Bugaz, Odesa Region. 2021. 157 p.

Kovalev AI. The role of higher-order aberrations in the stabilizing effect of orthokeratological correction of myopia in children and adolescents. In: Proceedings of the 7th Scientific-Practical Conference of Ophthalmologists in Chișinău with National and International Participation, "Actualități în Oftalmologie"; 2022 Apr 8-9; Chișinău, Republic of Moldova. Sănătate Publică, Economie şi Management în Medicină. 2022. Available from: https://revistaspemm.md/wp-content/uploads/2022/04/TIPAR_Actuslitati-in-oftalmologie-30-martie-2022.pdf

Tsybulska TE. Functional, biometric, and biomechanical changes in eye parameters in children with myopia: features of treatment and optical correction [dissertation abstract]. Kyiv (Ukraine): 2020. Ukrainian.

Holmes M, Liu M, Singh S. Retrospective Analysis of Axial Length Changes in Overnight Orthokeratology in an Academic Myopia Control Clinic. Optom Vis Sci. 2023 Sep 1;100(9):597-605. https://doi.org/10.1097/OPX.0000000000002060

Zhang Z, Chen Z, Chen Z, Zhou J, Zeng L, Xue F, et al. Change in Corneal Power Distribution in Orthokeratology: A Predictor for the Change in Axial Length. Transl Vis Sci Technol. 2022 Feb 1;11(2):18. https://doi.org/10.1167/tvst.11.2.18

Published

2025-03-03

How to Cite

1.
Tsybulska T, Titkova O. Current optical methods for controlling progressive myopia control in children: a review. J.ophthalmol. (Ukraine) [Internet]. 2025 Mar. 3 [cited 2025 Mar. 10];(1):54-9. Available from: http://ua.ozhurnal.com/index.php/files/article/view/231