Pathomorphological comparison of human pterygium and its experimental model

Authors

  • E. V. Maltsev State Institution The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine, Odessa, (Ukraine)
  • V. Ya. Usov State Institution The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine, Odessa, (Ukraine)
  • N. Yu. Krytsun The Ivano-Frankivsk National Medical University; Ivano-Frankivsk (Ukraine)

DOI:

https://doi.org/10.31288/oftalmolzh201454045

Keywords:

pterygium, pterygium model, morphology

Abstract

Objective: to conduct histological parallels between human pterygium and modeled by us in rabbits degenerative — proliferative process associated with the growth of the conjunctiva to the cornea, as close as possible to clinical manifestations of pterygium.

Results. We have developed in rabbits a model of degenerative and proliferative growth of the conjunctiva to the cornea (pterygium model) virtually identifies in histological structure of human pterygium tissue. And it allows not only to use this model for development new methods of surgical treatment of pterygium, but also to recommend it for studing various issues of pathogenesis and treatment of this eye disease.

References

1. Bilalov EN, Bakhritdinova FA Local microcirculation with primary pterygium according to fluorescein-angiographic studies. Vestn oftalmol. 2005; 6:14-6. Russian.

2. Volokhovskaya ZP, Bairammuradov RA, Gapurova GN. Conjunctival epithelial atypia on the place of remote pterygium. Zdravookhraneniie Turkmenistana. 1988; 6 (342):19- 22. Russian.

3. Volokhovskaya ZP. Morphological changes of the conjunctival microcirculation in pterygium. Zdravookhraneniie Turkmenistana. 1992; 3:40-4. Russian.

4. Kanyukov VN, Stadnikov AA, Lomukhina EA. Morphological analysis of pterygium. Proceedings of International scient. Conf., dedicated to 100 ann. Of acad. NA Puchkovskaya. 29- 30 May, 2008. Odessa, 2008. 363.

5. Kanyukov VN, Stadnikov AA, Lomukhina EA. Morpho functional characteristic of pterygium. Proceedings of IX Congress MAM Morphology. 2008. 58.

6. Maltsev EV, Usov VYa, Kritsun NYu. The pterygium modeling. Oftalmol Zh. 2013; 2:79- 82. Ukrainian. https://doi.org/10.31288/oftalmolzh201327982

7. Maltsev EV, Usov VYa, Kritsun NYu. Pathomorphological features of corneal-limbal zone in experimental animals when modeling degenerative proliferative processes associated with the growth of the conjunctiva on the cornea. Oftalmol Zh. 2013; 2:79- 82. Ukrainian

8. Titarenko ZD, Gonchar PF, Titarenko IV. Pterygium. Kishinev; 1992. 86 p.

9. Dzunic B, Jovanovich P, Vaselinovic D. Analysis of pathophysiological characteristics of pterygium. Bosnian J. basic medical sciences. 2010; 10(4):307- 13.https://doi.org/10.17305/bjbms.2010.2677

10.Golu T, Mogoanta L, Streba CT, Pirici DN, Malaescu D, Mateescu GO. Pterygium: histological and immunohistochemical aspects. Rom J Morphol. Embryol. 2011; 52(1):153- 8.

11.Mohammad I. Treatment of pterygium. Ann. Afr. Medicine. 2011; 10(3):197-203. https://doi.org/10.4103/1596-3519.84695

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Published

2014-10-30

Issue

No. 5 (2014): Journal of Ophthalmology (Ukraine)

Section

Experimental Studies

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Copyright (c) 2014 Е. В. Мальцев, В. Я. Усов, Н. Ю. Крицун

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