Structural changes of the cranial part of the optic nerve in traumatic injury of its orbital part in experiment
DOI:
https://doi.org/10.31288/oftalmolzh20146101105Keywords:
traumatic optic neuropathy, morphometric examination, violation of axon's flow, swelling of the myelin sheathAbstract
The role of compression factors on the formation of secondary degenerative factors and anti- and retrograde parts of the optic nerve in traumatic injuries insufficiently studied.
The aim of the study was to clarify the morphological features of traumatic anteh-rand injuries experiment.
Material and methods. The simulation of traumatic injury of the optic nerve was performed on 11 rabbits weighing 3.5—4.0 kg. The control group included 12 healthy rabbits. There were used cranial morphometric examinations of the optic nerve in both eyes injured (on day 14 after injury) and control animals.
Results. The study foundperiaksonal degeneration of cranial optic nerve, that was manifested violation of axon's flow the progress axial cylinders that arise as a re¬sult of swelling of myelin sheath.
Conclusions. Thus, structural changes of the optic nerve cranial confirmed light and ultra structural studies, data morphometry and there to the damage hemo-dynamic nerve may serve as a basis for further studies of the pathogenesis and development of treatment strategy traumatic optic neuropathy in the experiment.
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